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Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival
Increased β-cell death coupled with the inability to replicate existing β-cells drives the decline in β-cell mass observed in the progression of both major forms of diabetes. Understanding endogenous mechanisms of islet cell survival could have considerable value for the development of novel strateg...
Autores principales: | Hayes, Heather L., Peterson, Brett S., Haldeman, Jonathan M., Newgard, Christopher B., Hohmeier, Hans E., Stephens, Samuel B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315295/ https://www.ncbi.nlm.nih.gov/pubmed/28212395 http://dx.doi.org/10.1371/journal.pone.0172567 |
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