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RNAi for contactin 2 inhibits proliferation of U87-glioma stem cells by downregulating AICD, EGFR, and HES1

Glioblastoma is the most common form of malignant brain tumors and has a poor prognosis. Glioma stem cells (GSCs) are thought to be responsible for the aberrant proliferation and invasion. Targeting the signaling pathways that promote proliferation in GSCs is one of the strategies for glioma treatme...

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Detalles Bibliográficos
Autores principales: Guo, Yang, Zhang, Peidong, Zhang, Hongtian, Zhang, Peng, Xu, Ruxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315346/
https://www.ncbi.nlm.nih.gov/pubmed/28243115
http://dx.doi.org/10.2147/OTT.S113390