Unifying view of mechanical and functional hotspots across class A GPCRs

G protein-coupled receptors (GPCRs) are the largest superfamily of signaling proteins. Their activation process is accompanied by conformational changes that have not yet been fully uncovered. Here, we carry out a novel comparative analysis of internal structural fluctuations across a variety of rec...

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Detalles Bibliográficos
Autores principales: Ponzoni, Luca, Rossetti, Giulia, Maggi, Luca, Giorgetti, Alejandro, Carloni, Paolo, Micheletti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315405/
https://www.ncbi.nlm.nih.gov/pubmed/28158180
http://dx.doi.org/10.1371/journal.pcbi.1005381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315405/
https://www.ncbi.nlm.nih.gov/pubmed/28158180
http://dx.doi.org/10.1371/journal.pcbi.1005381

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