Cargando…

Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci

Juvenile dermatomyositis (JDM) is a chronic inflammatory myopathy and vasculopathy driven by genetic and environmental influences. Here, we investigated the genetic underpinnings of an analogous, spontaneous disease of dogs also termed dermatomyositis (DMS). As in JDM, we observed a significant asso...

Descripción completa

Detalles Bibliográficos
Autores principales: Evans, Jacquelyn M., Noorai, Rooksana E., Tsai, Kate L., Starr-Moss, Alison N., Hill, Cody M., Anderson, Kendall J., Famula, Thomas R., Clark, Leigh Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315411/
https://www.ncbi.nlm.nih.gov/pubmed/28158183
http://dx.doi.org/10.1371/journal.pgen.1006604