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Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci
Juvenile dermatomyositis (JDM) is a chronic inflammatory myopathy and vasculopathy driven by genetic and environmental influences. Here, we investigated the genetic underpinnings of an analogous, spontaneous disease of dogs also termed dermatomyositis (DMS). As in JDM, we observed a significant asso...
Autores principales: | Evans, Jacquelyn M., Noorai, Rooksana E., Tsai, Kate L., Starr-Moss, Alison N., Hill, Cody M., Anderson, Kendall J., Famula, Thomas R., Clark, Leigh Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315411/ https://www.ncbi.nlm.nih.gov/pubmed/28158183 http://dx.doi.org/10.1371/journal.pgen.1006604 |
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