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HMGB1 Induces an Inflammatory Response in the Chorioamniotic Membranes That Is Partially Mediated by the Inflammasome

Spontaneous preterm labor occurs in two subsets of patients with sterile intra-amniotic inflammation, a process induced by alarmins such as high-mobility group box-1 (HMGB1). Inflammasomes are implicated in the process of spontaneous preterm labor. Therefore, we investigated whether HMGB1 initiates...

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Detalles Bibliográficos
Autores principales: Plazyo, Olesya, Romero, Roberto, Unkel, Ronald, Balancio, Amapola, Mial, Tara N., Xu, Yi, Dong, Zhong, Hassan, Sonia S., Gomez-Lopez, Nardhy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315428/
https://www.ncbi.nlm.nih.gov/pubmed/27806943
http://dx.doi.org/10.1095/biolreprod.116.144139