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Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress

Major depression is a prevalent emotion disorder. Chronic stressful life in genetically susceptible individuals is presumably a major etiology that leads to neuron and synapse atrophy in the limbic system. Molecular mechanisms underlying the pathological changes remain elusive. Mice were treated by...

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Detalles Bibliográficos
Autores principales: Ma, K, Xu, A, Cui, S, Sun, M-R, Xue, Y-C, Wang, J-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315548/
https://www.ncbi.nlm.nih.gov/pubmed/27701406
http://dx.doi.org/10.1038/tp.2016.181