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Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity

Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the bloodstream. Major depressive disorder has been associated with an increased amount of mtDNA in leukocytes from saliva sample...

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Detalles Bibliográficos
Autores principales: Lindqvist, D, Fernström, J, Grudet, C, Ljunggren, L, Träskman-Bendz, L, Ohlsson, L, Westrin, Å
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315562/
https://www.ncbi.nlm.nih.gov/pubmed/27922635
http://dx.doi.org/10.1038/tp.2016.236