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Cytotoxic Effects of Dimorfolido-N-Trichloroacetylphosphorylamide and Dimorfolido-N-Benzoylphosphorylamide in Combination with C(60) Fullerene on Leukemic Cells and Docking Study of Their Interaction with DNA

Dimorfolido-N-trichloroacetylphosphorylamide (HL1) and dimorfolido-N-benzoylphosphorylamide (HL2) as representatives of carbacylamidophosphates were synthesized and identified by the methods of IR, (1)H, and (31)P NMR spectroscopy. In vitro HL1 and HL2 at 1 mM concentration caused cell specific and...

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Detalles Bibliográficos
Autores principales: Prylutska, S., Grynyuk, I., Grebinyk, A., Hurmach, V., Shatrava, Iu., Sliva, T., Amirkhanov, V., Prylutskyy, Yu., Matyshevska, O., Slobodyanik, M., Frohme, M., Ritter, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315654/
https://www.ncbi.nlm.nih.gov/pubmed/28235359
http://dx.doi.org/10.1186/s11671-017-1893-3