Prospective Analysis in GIST Patients on the Role of Alpha-1 Acid Glycoprotein in Imatinib Exposure

BACKGROUND: For imatinib, a relationship between systemic exposure and clinical outcome has been suggested. Importantly, imatinib concentrations are not stable and decrease over time, for which several mechanisms have been suggested. In this study, we investigated if a decrease in alpha-1 acid glyco...

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Detalles Bibliográficos
Autores principales: Bins, Sander, Eechoute, Karel, Kloth, Jacqueline S. L., de Man, Femke M., Oosten, Astrid W., de Bruijn, Peter, Sleijfer, Stefan, Mathijssen, Ron H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315737/
https://www.ncbi.nlm.nih.gov/pubmed/27461250
http://dx.doi.org/10.1007/s40262-016-0441-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315737/
https://www.ncbi.nlm.nih.gov/pubmed/27461250
http://dx.doi.org/10.1007/s40262-016-0441-0

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