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A global characterization of the translational and transcriptional programs induced by methionine restriction through ribosome profiling and RNA-seq

BACKGROUND: Among twenty amino acids, methionine has a special role as it is coded by the translation initiation codon and methionyl-tRNAi (Met-tRNAi) is required for the assembly of the translation initiation complex. Thus methionine may play a special role in global gene regulation. Methionine has...

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Detalles Bibliográficos
Autores principales: Zou, Ke, Ouyang, Qi, Li, Hao, Zheng, Jiashun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316152/
https://www.ncbi.nlm.nih.gov/pubmed/28212626
http://dx.doi.org/10.1186/s12864-017-3483-2