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Bmp-12 activates tenogenic pathway in human adipose stem cells and affects their immunomodulatory and secretory properties
BACKGROUND: Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplantation. However, BMPs belong to pleiotropic TGF-β superfamily and have diverse e...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316159/ https://www.ncbi.nlm.nih.gov/pubmed/28214472 http://dx.doi.org/10.1186/s12860-017-0129-9 |