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Using a vector pool containing variable-strength promoters to optimize protein production in Yarrowia lipolytica

BACKGROUND: The yeast Yarrowia lipolytica is an increasingly common biofactory. To enhance protein expression, several promoters have been developed, including the constitutive TEF promoter, the inducible POX2 promotor, and the hybrid hp4d promoter. Recently, new hp4d-inspired promoters have been cr...

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Detalles Bibliográficos
Autores principales: Dulermo, Rémi, Brunel, François, Dulermo, Thierry, Ledesma-Amaro, Rodrigo, Vion, Jérémy, Trassaert, Marion, Thomas, Stéphane, Nicaud, Jean-Marc, Leplat, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316184/
https://www.ncbi.nlm.nih.gov/pubmed/28212656
http://dx.doi.org/10.1186/s12934-017-0647-3