Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G

Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies targeting aquaporin-4 (AQP4-IgG) on astrocytes. We rep...

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Detalles Bibliográficos
Autores principales: Yao, Xiaoming, Verkman, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316191/
https://www.ncbi.nlm.nih.gov/pubmed/28212662
http://dx.doi.org/10.1186/s40478-017-0417-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316191/
https://www.ncbi.nlm.nih.gov/pubmed/28212662
http://dx.doi.org/10.1186/s40478-017-0417-9

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