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miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1

BACKGROUND: Evidence is accumulating to link cancer stem cells to the pathogenesis and progression of osteosarcoma. The aim of this study is to investigate the role of miR-335 in osteosarcoma stem cells. METHODS: Tumor spheroid culture and flow cytometry were applied to screen out osteosarcoma stem...

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Detalles Bibliográficos
Autores principales: Guo, Xiaodong, Yu, Ling, Zhang, Zhengpei, Dai, Guo, Gao, Tian, Guo, Weichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316195/
https://www.ncbi.nlm.nih.gov/pubmed/28239298
http://dx.doi.org/10.1186/s12935-017-0398-6