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miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1
BACKGROUND: Evidence is accumulating to link cancer stem cells to the pathogenesis and progression of osteosarcoma. The aim of this study is to investigate the role of miR-335 in osteosarcoma stem cells. METHODS: Tumor spheroid culture and flow cytometry were applied to screen out osteosarcoma stem...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316195/ https://www.ncbi.nlm.nih.gov/pubmed/28239298 http://dx.doi.org/10.1186/s12935-017-0398-6 |