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High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5

BACKGROUND: Claudins are a family of integral membrane proteins and are components of tight junctions (TJs). Many TJ proteins are known to tighten the cell structure and maintain a barrier. Claudin-2 forms gated paracellular channels and allows sodium ions and other small positively charged ions to...

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Detalles Bibliográficos
Autores principales: Abu-Farsakh, Sohaib, Wu, Tongtong, Lalonde, Amy, Sun, Jun, Zhou, Zhongren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316202/
https://www.ncbi.nlm.nih.gov/pubmed/28212604
http://dx.doi.org/10.1186/s12876-017-0590-0