An adaptive variant of TRIB2, rs1057001, is associated with higher expression levels of thermogenic genes in human subcutaneous and visceral adipose tissues

BACKGROUND: An obesity-related single-nucleotide polymorphism (SNP) of the Tribbles pseudokinase 2 gene (TRIB2) was shown to have underwent adaptive evolution in the last glacial period, suggesting a selective advantage of this SNP in human populations in cold environments. In order to verify this h...

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Detalles Bibliográficos
Autores principales: Nakayama, Kazuhiro, Iwamoto, Sadahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316227/
https://www.ncbi.nlm.nih.gov/pubmed/28212671
http://dx.doi.org/10.1186/s40101-017-0132-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316227/
https://www.ncbi.nlm.nih.gov/pubmed/28212671
http://dx.doi.org/10.1186/s40101-017-0132-z

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