Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening

PURPOSE: To assess exome data for pre-emptive pharmacogenetic screening for 203 clinically-relevant pharmacogenetic variant positions from the Pharmacogenomics Knowledgebase and Clinical Pharmacogenetics Implementation Consortium and identify copy number variants (CNVs) in CYP2D6. METHODS: We examin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ng, David, Hong, Celine S., Singh, Larry N., Johnston, Jennifer J., Mullikin, James C., Biesecker, Leslie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316383/
https://www.ncbi.nlm.nih.gov/pubmed/27537706
http://dx.doi.org/10.1038/gim.2016.105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316383/
https://www.ncbi.nlm.nih.gov/pubmed/27537706
http://dx.doi.org/10.1038/gim.2016.105

Ejemplares similares