Outgroup, alignment and modelling improvements indicate that two TNFSF13-like genes existed in the vertebrate ancestor

The molecular machinery required for lymphocyte development and differentiation appears to have emerged concomitantly with distinct B- and T-like lymphocyte subsets in the ancestor of all vertebrates. The TNFSF superfamily (TNFSF) members BAFF (TNFSF13/Blys) and APRIL (TNFSF13) are key regulators of...

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Detalles Bibliográficos
Autores principales: Redmond, Anthony K ., Pettinello, Rita, Dooley, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316386/
https://www.ncbi.nlm.nih.gov/pubmed/28070614
http://dx.doi.org/10.1007/s00251-016-0967-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316386/
https://www.ncbi.nlm.nih.gov/pubmed/28070614
http://dx.doi.org/10.1007/s00251-016-0967-1

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