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Outgroup, alignment and modelling improvements indicate that two TNFSF13-like genes existed in the vertebrate ancestor
The molecular machinery required for lymphocyte development and differentiation appears to have emerged concomitantly with distinct B- and T-like lymphocyte subsets in the ancestor of all vertebrates. The TNFSF superfamily (TNFSF) members BAFF (TNFSF13/Blys) and APRIL (TNFSF13) are key regulators of...
Autores principales: | Redmond, Anthony K ., Pettinello, Rita, Dooley, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316386/ https://www.ncbi.nlm.nih.gov/pubmed/28070614 http://dx.doi.org/10.1007/s00251-016-0967-1 |
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