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In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice

We describe a two-photon microscopy-based method to evaluate the in vivo systemic transport of compounds. This method comprises imaging of the intact liver, kidney and intestine, the main organs responsible for uptake and elimination of xenobiotics and endogenous molecules. The image quality of the...

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Detalles Bibliográficos
Autores principales: Reif, Raymond, Ghallab, Ahmed, Beattie, Lynette, Günther, Georgia, Kuepfer, Lars, Kaye, Paul M., Hengstler, Jan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316407/
https://www.ncbi.nlm.nih.gov/pubmed/27999878
http://dx.doi.org/10.1007/s00204-016-1906-5