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Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination

Diverse cellular stressors have been observed to trigger site-specific ubiquitination on several ribosomal proteins. However, the ubiquitin ligases, biochemical consequences, and physiologic pathways linked to these modifications are not known. Here, we show in mammalian cells that the ubiquitin lig...

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Detalles Bibliográficos
Autores principales: Juszkiewicz, Szymon, Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316413/
https://www.ncbi.nlm.nih.gov/pubmed/28065601
http://dx.doi.org/10.1016/j.molcel.2016.11.039