Chenodeoxycholic Acid Derivative HS-1200 Inhibits Hepatocarcinogenesis and Improves Liver Function in Diethylnitrosamine-Exposed Rats by Downregulating MTH1

Aim. To investigate the effects of HS-1200 on liver tumorigenesis and liver function in a diethylnitrosamine- (DEN-) induced hepatocellular carcinoma (HCC) rat model. Methods. Rats were randomly assigned into five groups: control, HS-1200, HCC, HCC + low dose HS-1200, and HCC + high dose HS-1200 gro...

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Detalles Bibliográficos
Autores principales: Xu, Miao, Zhao, Qi, Shao, Donghui, Liu, Hui, Qi, Jianni, Qin, Chengyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316462/
https://www.ncbi.nlm.nih.gov/pubmed/28261604
http://dx.doi.org/10.1155/2017/1465912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316462/
https://www.ncbi.nlm.nih.gov/pubmed/28261604
http://dx.doi.org/10.1155/2017/1465912

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