Cargando…
Chenodeoxycholic Acid Derivative HS-1200 Inhibits Hepatocarcinogenesis and Improves Liver Function in Diethylnitrosamine-Exposed Rats by Downregulating MTH1
Aim. To investigate the effects of HS-1200 on liver tumorigenesis and liver function in a diethylnitrosamine- (DEN-) induced hepatocellular carcinoma (HCC) rat model. Methods. Rats were randomly assigned into five groups: control, HS-1200, HCC, HCC + low dose HS-1200, and HCC + high dose HS-1200 gro...
Autores principales: | Xu, Miao, Zhao, Qi, Shao, Donghui, Liu, Hui, Qi, Jianni, Qin, Chengyong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316462/ https://www.ncbi.nlm.nih.gov/pubmed/28261604 http://dx.doi.org/10.1155/2017/1465912 |
Ejemplares similares
-
Anticancer effect of caudatin in diethylnitrosamine-induced hepatocarcinogenesis in rats
por: Song, Jie, et al.
Publicado: (2020) -
Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice
por: Hara, A, et al.
Publicado: (2000) -
Null anticarcinogenic effect of silymarin on diethylnitrosamine-induced hepatocarcinogenesis in rats
por: IMAMOTO, RYU, et al.
Publicado: (2014) -
Metformin inhibits early stage diethylnitrosamine-induced hepatocarcinogenesis in rats
por: JO, WOORI, et al.
Publicado: (2016) -
Tumor Promoting Effects of Sulforaphane on Diethylnitrosamine-Induced Murine Hepatocarcinogenesis
por: Zheng, Jie, et al.
Publicado: (2022)