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TLR7 Deficiency Leads to TLR8 Compensative Regulation of Immune Response against JEV in Mice
Japanese encephalitis virus (JEV) is a highly fatal pathogen to human beings. Toll-like receptor 7 (TLR7) plays a role as the first host defense against most single-stranded RNA flaviviruses. This study aims to investigate the role of TLR7 in inducing adaptive immune response in mice against JEV. In...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316529/ https://www.ncbi.nlm.nih.gov/pubmed/28265274 http://dx.doi.org/10.3389/fimmu.2017.00160 |