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The Ratio of 2-AG to Its Isomer 1-AG as an Intrinsic Fine Tuning Mechanism of CB1 Receptor Activation

Endocannabinoids are pleiotropic lipid messengers that play pro-homeostatic role in cellular physiology by strongly influencing intracellular Ca(2+) concentration through the activation of cannabinoid receptors. One of the best-known endocannabinoid ‘2-AG’ is chemically unstable in aqueous solutions...

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Detalles Bibliográficos
Autores principales: Dócs, Klaudia, Mészár, Zoltán, Gonda, Sándor, Kiss-Szikszai, Attila, Holló, Krisztina, Antal, Miklós, Hegyi, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316530/
https://www.ncbi.nlm.nih.gov/pubmed/28265242
http://dx.doi.org/10.3389/fncel.2017.00039