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APP—A Novel Player within the Presynaptic Active Zone Proteome

The amyloid precursor protein (APP) was discovered in the 1980s as the precursor protein of the amyloid A4 peptide. The amyloid A4 peptide, also known as A-beta (Aβ), is the main constituent of senile plaques implicated in Alzheimer’s disease (AD). In association with the amyloid deposits, increasin...

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Detalles Bibliográficos
Autores principales: Weingarten, Jens, Weingarten, Melanie, Wegner, Martin, Volknandt, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316543/
https://www.ncbi.nlm.nih.gov/pubmed/28265241
http://dx.doi.org/10.3389/fnmol.2017.00043