Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast

The onset of anaphase is triggered by activation of the anaphase-promoting complex/cyclosome (APC/C) following silencing of the spindle assembly checkpoint (SAC). APC/C triggers ubiquitination of Securin and Cyclin B, which leads to loss of sister chromatid cohesion and inactivation of Cyclin B/Cdk1...

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Detalles Bibliográficos
Autores principales: Meadows, John C., Lancaster, Theresa C., Buttrick, Graham J., Sochaj, Alicja M., Messin, Liam J., del Mar Mora-Santos, Maria, Hardwick, Kevin G., Millar, Jonathan B.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316559/
https://www.ncbi.nlm.nih.gov/pubmed/28178520
http://dx.doi.org/10.1016/j.celrep.2017.01.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316559/
https://www.ncbi.nlm.nih.gov/pubmed/28178520
http://dx.doi.org/10.1016/j.celrep.2017.01.032

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