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Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
The development of a successful lineage reprogramming strategy of liver to pancreas holds promises for the treatment and potential cure of diabetes. The liver is an ideal tissue source for generating pancreatic cells, because of its close developmental origin with the pancreas and its regenerative a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316826/ https://www.ncbi.nlm.nih.gov/pubmed/28193997 http://dx.doi.org/10.1038/ncomms14127 |