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CCR7 deficient inflammatory Dendritic Cells are retained in the Central Nervous System

Dendritic cells (DC) accumulate in the CNS during neuroinflammation, yet, how these cells contribute to CNS antigen drainage is still unknown. We have previously shown that after intracerebral injection, antigen-loaded bone marrow DC migrate to deep cervical lymph nodes where they prime antigen-spec...

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Detalles Bibliográficos
Autores principales: Clarkson, Benjamin D., Walker, Alec, Harris, Melissa G., Rayasam, Aditya, Hsu, Martin, Sandor, Matyas, Fabry, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316931/
https://www.ncbi.nlm.nih.gov/pubmed/28216674
http://dx.doi.org/10.1038/srep42856