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Mangiferin from Pueraria tuberosa reduces inflammation via inactivation of NLRP3 inflammasome

Recent reports have demonstrated the role of phyto-constituents in modulating inflammatory responses. Mangiferin isolated from Mangifera indica is known to induce potent anti-oxidative, anti-diabetic and anti-inflammatory activity. However, the molecular mechanism of its anti-inflammatory activity i...

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Detalles Bibliográficos
Autores principales: Bulugonda, Ramakrishna K., kumar, Kotha Anil, Gangappa, D., Beeda, Harshavardhan, Philip, Gundala Harold, Muralidhara Rao, Dowlathabad, Faisal, Syed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316935/
https://www.ncbi.nlm.nih.gov/pubmed/28218280
http://dx.doi.org/10.1038/srep42683