Cargando…

A 3′-5′ exonuclease activity embedded in the helicase core domain of Candida albicans Pif1 helicase

3′-5′ exonucleases are frequently found to be associated to polymerases or helicases domains in the same enzyme or could function as autonomous entities. Here we uncovered that Candida albicans Pif1 (CaPif1) displays a 3′-5′ exonuclease activity besides its main helicase activity. These two latter a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Xiao-Bin, Zhang, Bo, Bazeille, Nicolas, Yu, Ying, Liu, Na-Nv, René, Brigitte, Mauffret, Olivier, Xi, Xu-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316945/
https://www.ncbi.nlm.nih.gov/pubmed/28216645
http://dx.doi.org/10.1038/srep42865