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Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei

Melioidosis, caused by Burkholderia pseudomallei, is endemic in northeastern Thailand and Northern Australia. Severe septicemic melioidosis is associated with high levels of pro-inflammatory cytokines and is correlated with poor clinical outcomes. IL-10 is an immunoregulatory cytokine, which in othe...

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Detalles Bibliográficos
Autores principales: Kessler, Bianca, Rinchai, Darawan, Kewcharoenwong, Chidchamai, Nithichanon, Arnone, Biggart, Rachael, Hawrylowicz, Catherine M., Bancroft, Gregory J., Lertmemongkolchai, Ganjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316963/
https://www.ncbi.nlm.nih.gov/pubmed/28216665
http://dx.doi.org/10.1038/srep42791