Cargando…
A pan-cancer analysis of secreted Frizzled-related proteins: re-examining their proposed tumour suppressive function
Secreted frizzled-related proteins (SFRPs), containing five family members (SFRPs 1–5) are putative extracellular Wnt inhibitors. Given their abilities to inhibit Wnt signalling, as well as the loss of SFRP1 in many cancers, this family is generally considered to be tumour suppressive. In this study...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316967/ https://www.ncbi.nlm.nih.gov/pubmed/28218291 http://dx.doi.org/10.1038/srep42719 |