Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development

In a mouse model of temporal lobe epilepsy, multicellular calcium imaging revealed that disease emergence was accompanied by massive amplification in the normally sparse, afferent stimulation-induced activation of hippocampal dentate granule cells. Patch recordings demonstrated reductions in local i...

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Detalles Bibliográficos
Autores principales: Dengler, Christopher G., Yue, Cuiyong, Takano, Hajime, Coulter, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316990/
https://www.ncbi.nlm.nih.gov/pubmed/28218241
http://dx.doi.org/10.1038/srep42090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316990/
https://www.ncbi.nlm.nih.gov/pubmed/28218241
http://dx.doi.org/10.1038/srep42090

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