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Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development
In a mouse model of temporal lobe epilepsy, multicellular calcium imaging revealed that disease emergence was accompanied by massive amplification in the normally sparse, afferent stimulation-induced activation of hippocampal dentate granule cells. Patch recordings demonstrated reductions in local i...
Autores principales: | Dengler, Christopher G., Yue, Cuiyong, Takano, Hajime, Coulter, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316990/ https://www.ncbi.nlm.nih.gov/pubmed/28218241 http://dx.doi.org/10.1038/srep42090 |
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