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Mechanistic Investigation on ROS Resistance of Phosphorothioated DNA
Phosphorothioated DNA (PT-DNA) exhibits a mild anti-oxidant property both in vivo and in vitro. It was found that 8-OHdG and ROS levels were significantly lower in dnd+ (i.e. S(+)) E. coli., compared to a dnd− (i.e. S(−)) strain. Furthermore, different from traditional antioxidants, phosphorothioate...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316992/ https://www.ncbi.nlm.nih.gov/pubmed/28216673 http://dx.doi.org/10.1038/srep42823 |