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New insight into chondroitin and heparosan-like capsular polysaccharide synthesis by profiling of the nucleotide sugar precursors

Escherichia coli K4 and K5 capsular polysaccharides (K4 and K5 CPSs) have been used as starting material for the biotechnological production of chondroitin sulfate (CS) and heparin (HP) respectively. The CPS covers the outer cell wall but in late exponential or stationary growth phase it is released...

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Detalles Bibliográficos
Autores principales: Restaino, Odile Francesca, di Lauro, Irene, Di Nuzzo, Rosaria, De Rosa, Mario, Schiraldi, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317027/
https://www.ncbi.nlm.nih.gov/pubmed/28104792
http://dx.doi.org/10.1042/BSR20160548