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S 38093, a histamine H(3) antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice
Strategies designed to increase adult hippocampal neurogenesis (AHN) may have therapeutic potential for reversing memory impairments. H(3) receptor antagonists/inverse agonists also may be useful for treating cognitive deficits. However, it remains unclear whether these ligands have effects on AHN....
Autores principales: | Guilloux, Jean-Philippe, Samuels, Benjamin A., Mendez-David, Indira, Hu, Alice, Levinstein, Marjorie, Faye, Charlène, Mekiri, Maryam, Mocaer, Elisabeth, Gardier, Alain M., Hen, René, Sors, Aurore, David, Denis J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317168/ https://www.ncbi.nlm.nih.gov/pubmed/28218311 http://dx.doi.org/10.1038/srep42946 |
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