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Corneal permeation properties of a charged lipid nanoparticle carrier containing dexamethasone

Drug delivery carriers can maintain effective therapeutic concentrations in the eye. To this end, we developed lipid nanoparticles (L/NPs) in which the surface was modified with positively charged chitosan, which engaged in hydrogen bonding with the phospholipid membrane. We evaluated in vitro corne...

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Detalles Bibliográficos
Autores principales: Ban, Junfeng, Zhang, Yan, Huang, Xin, Deng, Guanghan, Hou, Dongzhi, Chen, Yanzhong, Lu, Zhufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317251/
https://www.ncbi.nlm.nih.gov/pubmed/28243093
http://dx.doi.org/10.2147/IJN.S126199