Utilization of Positive and Negative Controls to Examine Comorbid Associations in Observational Database Studies

BACKGROUND: Opportunities to leverage observational data for precision medicine research are hampered by underlying sources of bias and paucity of methods to handle resulting uncertainty. We outline an approach to account for bias in identifying comorbid associations between 2 rare genetic disorders...

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Detalles Bibliográficos
Autores principales: Desai, Jigar R., Hyde, Craig L., Kabadi, Shaum, St Louis, Matthew, Bonato, Vinicius, Katrina Loomis, A., Galaznik, Aaron, Berger, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318155/
https://www.ncbi.nlm.nih.gov/pubmed/27787351
http://dx.doi.org/10.1097/MLR.0000000000000640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318155/
https://www.ncbi.nlm.nih.gov/pubmed/27787351
http://dx.doi.org/10.1097/MLR.0000000000000640

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