Cargando…

Blood transcriptome based biomarkers for human circadian phase

Diagnosis and treatment of circadian rhythm sleep-wake disorders both require assessment of circadian phase of the brain’s circadian pacemaker. The gold-standard univariate method is based on collection of a 24-hr time series of plasma melatonin, a suprachiasmatic nucleus-driven pineal hormone. We d...

Descripción completa

Detalles Bibliográficos
Autores principales: Laing, Emma E, Möller-Levet, Carla S, Poh, Norman, Santhi, Nayantara, Archer, Simon N, Dijk, Derk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318160/
https://www.ncbi.nlm.nih.gov/pubmed/28218891
http://dx.doi.org/10.7554/eLife.20214