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Genome-wide chromatin accessibility, DNA methylation and gene expression analysis of histone deacetylase inhibition in triple-negative breast cancer

Triple-negative breast cancer (TNBC), especially the subset with a basal phenotype, represents the most aggressive subtype of breast cancer. Unlike other solid tumors, TNBCs harbor a low number of driver mutations. Conversely, we and others have demonstrated a significant impact of epigenetic altera...

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Detalles Bibliográficos
Autores principales: Bustos, Matias A., Salomon, Matthew P., Nelson, Nellie, Hsu, Sandy C., DiNome, Maggie L., Hoon, Dave S.B., Marzese, Diego M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318344/
https://www.ncbi.nlm.nih.gov/pubmed/28239551
http://dx.doi.org/10.1016/j.gdata.2017.01.002