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Disrupted neural activity patterns to novelty and effort in young adult APOE‐e4 carriers performing a subsequent memory task

INTRODUCTION: The APOE e4 allele has been linked to poorer cognitive aging and enhanced dementia risk. Previous imaging studies have used subsequent memory paradigms to probe hippocampal function in e4 carriers across the age range, and evidence suggests a pattern of hippocampal overactivation in yo...

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Detalles Bibliográficos
Autores principales: Evans, Simon, Dowell, Nicholas G., Tabet, Naji, King, Sarah L., Hutton, Samuel B., Rusted, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318365/
https://www.ncbi.nlm.nih.gov/pubmed/28239522
http://dx.doi.org/10.1002/brb3.612