A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma

In asthma, excessive bronchial narrowing associated with thickening of the airway smooth muscle (ASM) causes respiratory distress. Numerous pharmacological agents prevent experimental airway hyperresponsiveness (AHR) when delivered prophylactically. However, most fail to resolve this feature after d...

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Detalles Bibliográficos
Autores principales: Gendron, David R., Lecours, Pascale B., Lemay, Anne-Marie, Beaulieu, Marie-Josée, Huppé, Carole-Ann, Lee-Gosselin, Audrey, Flamand, Nicolas, Don, Anthony S., Bissonnette, Élyse, Blanchet, Marie-Renée, Laplante, Mathieu, Bourgoin, Sylvain G., Bossé, Ynuk, Marsolais, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318459/
https://www.ncbi.nlm.nih.gov/pubmed/28270767
http://dx.doi.org/10.3389/fphar.2017.00078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318459/
https://www.ncbi.nlm.nih.gov/pubmed/28270767
http://dx.doi.org/10.3389/fphar.2017.00078

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