Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra

Cerebral dopamine neurotrophic factor (CDNF) protects the nigrostriatal dopaminergic (DA) neurons in rodent models of Parkinson’s disease and restores DA circuitry when delivered after these neurons have begun to degenerate. These DA neurons have been suggested to transport striatal CDNF retrogradel...

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Detalles Bibliográficos
Autores principales: Mätlik, Kert, Vihinen, Helena, Bienemann, Ali, Palgi, Jaan, Voutilainen, Merja H., Booms, Sigrid, Lindahl, Maria, Jokitalo, Eija, Saarma, Mart, Huttunen, Henri J., Airavaara, Mikko, Arumäe, Urmas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318544/
https://www.ncbi.nlm.nih.gov/pubmed/28275710
http://dx.doi.org/10.1523/ENEURO.0128-16.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318544/
https://www.ncbi.nlm.nih.gov/pubmed/28275710
http://dx.doi.org/10.1523/ENEURO.0128-16.2017

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