Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies

OBJECTIVES: Designing studies with an internal pilot phase may optimise the use of pilot work to inform more efficient randomised controlled trials (RCTs). Careful selection of preagreed decision or ‘progression’ criteria at the juncture between the internal pilot and main trial phases provides a va...

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Detalles Bibliográficos
Autores principales: Avery, Kerry N L, Williamson, Paula R, Gamble, Carrol, O'Connell Francischetto, Elaine, Metcalfe, Chris, Davidson, Peter, Williams, Hywel, Blazeby, Jane M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Health Services Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318608/
https://www.ncbi.nlm.nih.gov/pubmed/28213598
http://dx.doi.org/10.1136/bmjopen-2016-013537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318608/
https://www.ncbi.nlm.nih.gov/pubmed/28213598
http://dx.doi.org/10.1136/bmjopen-2016-013537

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