An Endosomal NAADP-Sensitive Two-Pore Ca(2+) Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

Membrane contact sites are regions of close apposition between organelles that facilitate information transfer. Here, we reveal an essential role for Ca(2+) derived from the endo-lysosomal system in maintaining contact between endosomes and the endoplasmic reticulum (ER). Antagonizing action of the...

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Detalles Bibliográficos
Autores principales: Kilpatrick, Bethan S., Eden, Emily R., Hockey, Leanne N., Yates, Elizabeth, Futter, Clare E., Patel, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318655/
https://www.ncbi.nlm.nih.gov/pubmed/28199837
http://dx.doi.org/10.1016/j.celrep.2017.01.052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318655/
https://www.ncbi.nlm.nih.gov/pubmed/28199837
http://dx.doi.org/10.1016/j.celrep.2017.01.052

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