Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea

OBJECTIVES: Eluxadoline is a mixed μ-opioid receptor (OR) and κ-OR agonist and δ-OR antagonist, approved for the treatment of irritable bowel syndrome with diarrhea (IBS-D). This analysis evaluated the safety and tolerability of eluxadoline 75 and 100 mg twice daily (BID) in one Phase 2 (IBS-2001) a...

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Detalles Bibliográficos
Autores principales: Cash, Brooks D, Lacy, Brian E, Schoenfeld, Philip S, Dove, Leonard S, Covington, Paul S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Functional GI Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318664/
https://www.ncbi.nlm.nih.gov/pubmed/27922029
http://dx.doi.org/10.1038/ajg.2016.542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318664/
https://www.ncbi.nlm.nih.gov/pubmed/27922029
http://dx.doi.org/10.1038/ajg.2016.542

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