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Prefoldin 1 promotes EMT and lung cancer progression by suppressing cyclin A expression

Prefoldin (PFDN) is a co-chaperone protein that is primarily known for its classic cytoplasmic functions in the folding of actin and tubulin monomers during cytoskeletal assembly. Here, we report a marked increase in prefoldin subunit 1 (PFDN1) levels during the transforming growth factor (TGF)-β1-m...

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Detalles Bibliográficos
Autores principales: Wang, D, Shi, W, Tang, Y, Liu, Y, He, K, Hu, Y, Li, J, Yang, Y, Song, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318667/
https://www.ncbi.nlm.nih.gov/pubmed/27694898
http://dx.doi.org/10.1038/onc.2016.257